Contributions of chemistry and material sciences to the translational research: examples of the current research | Vestnik Tomskogo gosudarstvennogo universiteta. Chimia – Tomsk State University Journal of Chemistry. 2016. № 1(3).

Contributions of chemistry and material sciences to the translational research: examples of the current research

Translational research involves basic research, patient-oriented clinical research and population related research targeting to improve sustainably the public-health. New approaches to materials, preventions of disease, diagnostics and therapies access clinical trials in order to enhance steadily the therapeutic success for the affected patients. Essential requirements are the efficient partnership ofphysicians, researches in natural, biomedical and material sciences, and the medical device and pharmaceutical industry as well. Briefly outlined examples of the collaboration between the natural sciences in Tomsk and Muenster (Germany) and an orthopedic clinic and a radiation therapeutic/oncologic department (Muenster, Germany) demonstrate the contribution of chemistry and material sciences to the translational research.

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Keywords

трансляционные исследования, примеры сотрудничества, биоматериалы, “от скамьи к постели и обратно”, translational research, examples of the collaboration, biomaterials, "from bench to bedside and back again"

Authors

NameOrganizationE-mail
Kurzina Irina A.Tomsk State Universitykurzina99@mail.ru
Heinrich LotharWestphalian Wilhelms University of Muensterlothar.heinrich@uni-muenster.de
Всего: 2

References

NINDS Exploratory/developmental projects in translational research, program, NIH, announcement number: PAR-02-138, July 26, 2002.
Gregory S.G., Barlow K.F. The DNA sequence and biological annotation of human chromosome 1 / S.G. Gregory, K.F. Barlow u.a. // Nature. 2006. Vol. 441. P. 315-321.
Marincola M.J. Editorial: Translational Medicine: A two-way road // J. Transl. Med. 2003. Vol. 1. P. 1.
Zerhouni E. Medicine. The NIH Roadmap // Science. 2003. Vol. 302. P. 63-72.
Lee W.-H., Languino L.R., Hung M.-C., Dubinett S.M., Iczkowski K.A., Wang D. The launch of the American Journal of Translational Research // Am. J. Transl. Res. 2009. Vol. 1. P. 1.
The E.U. total health budget for framework 7 Available from: http://ec.europa.eu/research/fp7/index_en.cfm?pg=health.
Ukaz Prezidenta RF ot 7 maya 2012 g. N 598 "O sovershenstvovanii gosudarstvenniy poli-tiki v sphere zdravookhraneniya".
Pravitelstvo Rossiiskoi Phederazii, Rasporyazhenie ot 24 dekabrya 2012 g. no 2511-r.
Bickels J. et al. Distal femur resection with endoprosthetic reconstruction // Clin Orthop Relat Res. 2002. Vol. 400. P. 225-235.
Gosheger G., Gebert C., Ahrens H., Streitbuerger A., Winkelmann W., Hardes J. Endoprosthetic reconstruction in 250 patients with sarcoma // Clin Orthop Relat Res. 2006. Vol. 450. P. 164-171.
Website of IMPLANTCAST GmbH (Russian): www.implantcast.de/index.php?lang=ru.
Hardes J., von Eiff C., Streitbuerger A., Balke M., Budey T., Heinrichs M.P., Hauschild G., Ahrens H. Reduction of periprosthetic infection with silver-coated megaprostheses in patients with bone sarcoma // J. Surg Oncol. 2010. Vol. 101. Is. 5. P. 389-390.
Wang X., Herting G., Wallinder IO., Blomberg E. Adsorption of bovine serum albumin on silver surfaces enhances the release of silver at pH neutral conditions // Chem Phys. 2015. Vol. 17(28). P. 18524-18534.
Hussmann B. et al. Measurement of the Silver Ion Concentration in Wound Fluids after Implantation of Silver-Coated Megaprostheses: Correlation with the Clinical Outcome / B. Hussmann et al. // BioMed Research International. 2013. article ID 763096, 11 pages.
URL: http://dx.doi.org/10.1155/2013/763096.
Beroukas E. et al. Intraoperative electron beam radiotherapy followed by moderate doses of external beam radiotherapy in the treatment of resected soft tissue sarcomas of the extremities // J. BUON. 2004. Vol. 9. Is. 4. P. 391-398.
Singh J., Kaur M. Current Advances and Stretegies for Reducing the Side Effects of Radiation Therapies used for Various Types of Cancers // Int J Appl Biol and Pharm Tech. 2012. Vol. 3. Is. 1. P. 184-199.
Jolyon H., Hendry J.H., Jeremi B., Zubizarreta E.H. Normal tissue complications after radiation therapy, Rev Panam Salud Publica // Pan Am J Public Health. 2006. Vol. 20(2/3). P. 151-160.
Kumar B., Jha M.N., Bedford J.S., Prasad K.N. D-alpha-tocopheryl succinate (vitamin E) enhances radiation-induced chromosomal damage levels in human cancer cells, but reduces it in normal cells // J. Am. College of Nutr. 2002. Vol. 21. Is. 4. P. 339-343.
Pang Z., Han C. Review on Transdermal Drug Delivery Systems // J. Pharma & Drug Dev. 2014. Vol. 2. Is. 4. P. 1-10.
Bhowmick M., Sengodan T. Mechanisms, kinetics and mathematical modelling of trans-dermal permeation - an updated review // Int. J. Res. Dev. Pharm. L. Sci. 2013. Vol. 2. Is. 6. P. 636-641.
Sharma A., Saini S., Rana A. C. Transdermal Drug Delivery System: A Review // Int. J. Res. Pharm. and Biomed. Sc. 2013. Vol. 4(1). P. 286-292.
 Contributions of chemistry and material sciences to the translational research: examples of the current research | Vestnik Tomskogo gosudarstvennogo universiteta. Chimia – Tomsk State University Journal of Chemistry. 2016. № 1(3).

Contributions of chemistry and material sciences to the translational research: examples of the current research | Vestnik Tomskogo gosudarstvennogo universiteta. Chimia – Tomsk State University Journal of Chemistry. 2016. № 1(3).

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