Synthesis and study of some ester’s derivatives of 3α,7β-dihydroxy-3α,7β,12α-trihydroxy-5β-cholanic acid

This work presents the results of the synthesis of new esters of 3α,7β-dihydroxy and 3α,7β,12α-trihydroxy-5β-cholanic acid. At the present stage of the development of science all over the world, ways and methods of synthesis of new effective drugs are being sought. In this regard, the targeted synthesis of new classes of steroid compounds with biologically active properties is an urgent task for chemical scientists, pharmacists, pharmacologists and biochemists. Among the synthesized esters of cholanic acids, new litholytic, anti-inflammatory, antimicrobial, polycationic amphiphiles and other practically valuable materials have been identified. Of particular interest are the derivatives of cholanic acids, which have various functional groups, which facilitate the production on their basis of several other compounds with desired biological properties.

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