Neural networks in the diagnosis of malignant neoplasms by exhaled air | Vestnik Tomskogo gosudarstvennogo universiteta. Upravlenie, vychislitelnaja tehnika i informatika – Tomsk State University Journal of Control and Computer Science. 2025. № 73. DOI: 10.17223/19988605/73/14

Neural networks in the diagnosis of malignant neoplasms by exhaled air

The results of a study the set of neural network architectures with variable learning parameters for processing data from gas-analytical medical devices designed for noninvasive diagnosis of lung and upper respiratory tract cancer are considered. The algorithm provides structuring of the input pattern format for the neural network, taking into account the criterion of maximum information in the input data. Diagnostic data from gas-analytical medical devices are arrays of integer values of codes from analog-to-digital converters. The neural network data processing algorithm is implemented in the Python programming language. The study used digitized exhaled air samples from 154 people. For cases of separate differentiation of healthy volunteers, patients with lung and upper respiratory tract cancers, the neural network data processing algorithm showed an average accuracy exceeding 86%. Contribution of the authors: the authors contributed equally to this article. The authors declare no conflicts of interests.

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Keywords

data processing, classifier, artificial neural network, neural network architecture, input data format, input data optimization, learning parameters, differentiation feature, classifier efficiency

Authors

NameOrganizationE-mail
Obkhodskiy Artem V.National Research Tomsk Polytechnic Universityart707@yandex.ru
Kulbakin Denis E.Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Scienceskulbakin_d@mail.ru
Obkhodskaya Elena V.National Research Tomsk State Universityfil330a@yandex.ru
Lakonkin Vladislav S.National Research Tomsk Polytechnic University; Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciencesvsl13@tpu.ru
Rodionov Evgeniy O.Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences; Siberian State Medical Universityrodionov_eo@oncology.tomsk.ru
Sachkov Victor I.National Research Tomsk State Universityvicsachkov@gmail.com
Chernov Vladimir I.Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Scienceschernov@tnimc.ru
Choynzonov Evgeny L.Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Scienceschoynzonov@tnimc.ru
Всего: 8

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 Neural networks in the diagnosis of malignant neoplasms by exhaled air | Vestnik Tomskogo gosudarstvennogo universiteta. Upravlenie, vychislitelnaja tehnika i informatika – Tomsk State University Journal of Control and Computer Science. 2025. № 73. DOI: 10.17223/19988605/73/14

Neural networks in the diagnosis of malignant neoplasms by exhaled air | Vestnik Tomskogo gosudarstvennogo universiteta. Upravlenie, vychislitelnaja tehnika i informatika – Tomsk State University Journal of Control and Computer Science. 2025. № 73. DOI: 10.17223/19988605/73/14

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