NEW PRODUCTS TISSUE-ENGINEERING IN THE TREATMENT OF SPINAL CORD INJURY
The results of the use of chitosan-collagen substrates in the presence of growth factors and neuronal differentiation of mouse and human embryonic stem cells in treatment of complete anatomical fracture of the spinal cord in rats has been presented in the paper. It was demonstrated that transplantation of these substrates in the spinal cord of animals, leads to complete or partial recovery of motor, sensory and autonomic functions.
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Keywords
коллагенхитозановая матрица, нейрональные клеткипредшественники мыши и человека, индуцированные плюрипотентные стволовые клетки человека, трансплантация, анатомическое повреждение спинного мозга, функциональное восстановление, chitosancollagen substrate, mouse and human embryonic stem cells, transplantation, spinal cord injury, functional recoveryAuthors
Name | Organization | |
Bolshakov I. N. | bol.bol@mail.ru | |
Sergienko V. I. | ||
Kiselev S. L. | ||
Lagarkova M. A. | ||
Remigaylo A. A. | ||
Mikhaylov A. A. | ||
Prokopenko S. V. |
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Shutova M., Chestkov I., Bogomazova A., Lagarkova M., Kiselev S. L. Generation of iPS cells from human umbilical vein endothelial cells by lentiviral transduction, and their differentiation to neuronal lineage. In: Kaiming Ye and Sha Jin (eds.), Human Embryonic and Induced Pluripotent Stem Cells: Lineage-Specific Differentiation Protocols, Springer Protocols Handbooks, DOI 10.1007 / 978-1-61779-267-0_11, Springer Science + Business Media, LLC 2011.

NEW PRODUCTS TISSUE-ENGINEERING IN THE TREATMENT OF SPINAL CORD INJURY | Issues of reconstructive and plastic surgery. 2015. № 3 (54).
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