COMPARISON OF IMMUNOGENICITY OF THE SKIN AND MUSCLE TISSUE ON MODEL FACIAL ALLOGRAFT MUSCULOCUTANEUS FLAP IN THE EXPERIMENT | Issues of reconstructive and plastic surgery. 2016. № 3 (58). DOI: 10.17223/1814147/58/04

COMPARISON OF IMMUNOGENICITY OF THE SKIN AND MUSCLE TISSUE ON MODEL FACIAL ALLOGRAFT MUSCULOCUTANEUS FLAP IN THE EXPERIMENT

Restoring the integrity of the facial skin by a variety of skin plastic techniques do not always satisfy the requirements of a physician and a patient. In this regard, allograft facial area is sometimes the only option that can give a more complete result. This article describes an experimental research. Which analyses clinical and immunologуcal status rats recipients with facial allografts containing different volume of the skin and muscle tissue.

Download file

Counter downloads: 286

Keywords

фациальная аллотрансплантация, иммуносупрессивная терапия, кожно-мышечный лоскут, facial allotransplantation, immunosuppressive therapy, musculocutaneus flap

Authors

Name	Organization	E-mail
Aksenova S.A.		svetlanaaksenova1987@yandex.ru
Abzaleva G.R.
Volokh M.A.
Lila A.M.

Всего: 4

References

Siemionow M. Impact of reconstructive transplantation on the future of plastic and reconstructive surgery // Clin. Plast. Surg. - 2012. - V. 39. - P. 425-434.

Pomahac B., Diaz-Siso J.R., Bueno E.M. Evolution of indications for facial transplantation // J. Plast. Reconstr. Aesthet. Surg. - 2011. - V. 64. - P. 1410-1416.

Siemionow M., Ozturk C., Craniofac J. Face transplantation: outcomes, concerns, controversies, and future idirections // Surg. - 2012. - V. 23. - P. 254-259.

Li X.C., Turka L.A. An update on regulatory T cells in transplant tolerance and rejection // Nat. Rev. Nephrol. - 2010. - V. 6, № 10. - P. 577-583.

Murphy B.D., Zuker R.M., Borschel G.H. Vascularized composite allotransplantation: an update on medical and surgical progress and remaining challenge // J. Plast. Reconstr. Aesthet. Surg. - 2013. - V. 66. - P. 1449-1455.

Kuo Y.R. Chen C.C., Goto S., Lee I.E. Modulation of immune response and T cell regulation by donor adiposederived stem cells in a rodent hind-limb allotransplant model // Plast. Reconstr. Surg. - 2011. - V. 128. - P. 661-672.

Kim Y.H., Wee YM., Choi M.Y., Lim D.G., Kim S.C. Interleukin (IL)-10 inducedby CD11b(+) cell sand IL-10activated regulatory T cells playa role in immune modulation of mesenchymal stem cells in rat islet allografts // Mol. - 2011. - V. 17. - P. 697-708.