ANESTHESIA IN SWINES AS A MODEL IN BIOMEDICAL AND BIOTECHNOLOGICAL STUDIES
Swines are considered to be the best biological model of the human organism. Using swines in surgical experiments determines the necessity to develop the algorithm of anesthetic aid. Swines have no superficial veins therefore using some veterinary anesthetics (Zolazepam/Tiletamin, Xylazin) are the alternatives for sedation, rapid induction of anesthesia and analgesia. Basic anesthetics for rapid and induction and maintenance of anesthesia ( in presence of venous access) is Propofol. Droperidol is used for potentiation of analgetics and basic anesthetics. Tracheal intubation in swines is a difficult procedure because of anatomical specificity of upper respiratory tract. For successful intubation, both curved and straight large laryngoscopes (sizes 4 and 5) are needed. Besides, conicotomy and tracheostomy sets and laryngeal masks should be prepared before the procedure. Intubation is performed using the knife of Macintosh type and of Miller type. NSAID’s and Meditin are used for adequate analgesia. Putting central venous catheter may be fulfilled both by puncture and by section of internal jugular vein. To control arterial pressure, putting of arterial cannula in femoral, carotid or brachial arteries is recommended.
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Keywords
анестезиология, модельный объект, свиньи, anesthesiology, model, swinesAuthors
| Name | Organization | |
| Vachnadze D.I. | david1255@yandex.ru | |
| Breshenkov D.G. | ||
| Dydykin S.S. |
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