THE STORY OF ONE DISSERTATION RESEARCH

The paper is devoted to professor F.F. Saks (1918-1998), famous Russian surgeon and topographoanatomist, disciple of A.G. Savinykh, academician of the Academy of Medical Sciences of the USSR, one of the founders of surgery of esophageal cancer and cardiac cancer in the USSR. The dissertation research by professor F.F. Saks, which was devoted to anatomy and physiology of cardiac sphincter, stimulated the development of the absolutely new research field - functional morphology of digestive system sphincters. This research field was strongly supported by professor M.A. Medvedev, rector of the Tomsk Medical Institute (Siberian Medical University), corresponding member of the Academy of Medical Sciences of the USSR. The scientific tandem Medvedev-Saks became very efficient, and it enlisted a large number of followers from all over the USSR to this new research field. Recognition from many leading scientists in “sphincterology” came unexpectedly, from the Oxford University (Great Britain). In the early 2000s, the studies of sphincter zones in the upper and lower urinary tract, as well as the role of closing structures (arterioles) in regulation of capillary perfusion of tissues of free (denervated) microsurgical flaps were started in Tomsk. The analysis and synthesis of the results of these studies yielded the understanding that there is a universal mechanism in the activity of sphincters and pacemakers in regulation of movement of the contents [food bolus, urine bolus, systolic discharge] to the periphery: suppression of the neurogenic component of basal tone of smooth muscle of walls of lower sections of the corresponding functional system in advance of the peristaltic or pulse wave.

Keywords

Authors

References