ACUTE PANCREATITIS DUE TO PARATHYROID ADENOMA | Issues of reconstructive and plastic surgery. 2019. № 3 (70). DOI: 10.17223/1814147/70/06

ACUTE PANCREATITIS DUE TO PARATHYROID ADENOMA

The combination of primary hyperparathyroidism and acute pancreatitis is a rare pathology. Ectopic parathyroid adenomas in the mediastinum are the cause of primary hyperparathyroidism in 5 to 10% of cases. And theremoval of the adenoma ends in a cure for the disease. We consulted a 71-year-old woman with acute pancreatitis and elevated levels of blood calcium. During thestudy, using computed tomography, an ectopic thyroid adenoma was found in the mediastinum. The tumor is removed by collar access at the neck. After that, the levels of calcium and parathyroid hormone returned to normal. Acute pancreatitis in combination with elevated blood calcium levels should suggest the presence of possibleprimary hyperparathyroidism. And accurate preoperative diagnosis of the location of the adenoma using computedtomography of the neck is the key to successful surgical treatment.

Download file

Counter downloads: 64

Keywords

околощитовидная железа, эктопия, аденома, панкреатит, parathyroid gland, ectopia, adenoma, pancreatitis

Authors

Name	Organization	E-mail
Zubkov A.V.	Volgograd State Medical University	Zubkov.A.V.74.ru@mail.ru
Krayshkin A.I.	Volgograd State Medical University	krayushkin_ai@mail.ru
Giganurov I.R.	Volgograd State Medical University	jiganurov@mail.ru
Rybak Ye.N.	Volgograd State Medical University	ensoloncova@volgmed.ru

Всего: 4

References

Ewing P., Hardy J.D. The mediastinum. In: Glenn's Thoracic and Cardiovascular Surgery Volume 1. 5th edition. Edited by: Baue A.E., Geha A.S., Hammond G.L., Laks H., Naunheim K.S. Connecticut: Appleton and Lange. 1991:569-594.

Richards M.L., Bondeson A.G., Thompson N.W. Mediastinal parathyroid adenomas and carcinomas. In: General Thoracic Surgery Volume 2. 5th edition. Edited by: Shields T.W., LoCicero III J., Ponn R.B. Philadelphia: Lippincot Williams and Willkins. 2000:2383-2390.

Nguyen B.D. Parathyroid imaging with Tc-99m sestamibi planar and SPECT scintigraphy. Radiographics. 1999; 19:601-614.

Agarwal A., George R.K., Gupta S.K., Mishra S.K. Pancreatitis in patients with primary hyperparathyroidism. Indian J Gastroenterol. 2003, 22:224-225.

Shepherd J.J. Hyperparathyroidism presenting as pancreatitis or complicated by postoperative pancreatitis. Aust N Z J Surg. 1996; 66:85-87.

Koppelberg T., Bartsch D., Printz H., Hasse C., Rothmund M. Pancreatitis in primary hyperparathyroidism (pHPT) is a complication of advanced pHPT. Dtsch Med Wochenschr. 1994; 119:719-724.

Carnaille B., Oudar C., Pattou F., Combamale F., Rocha J., Proye C. Pancreatitis and primary hyperparathyroidism: forty cases. Aust N Z J Surg. 1998; 68:117-119.

Husova L., Senkyrik M., Lata J., Hrbkova V., Husa P., Dolina J., Podral M., Ourednicek P. Acute pancreatitis as the road to diagnosis of primary hyperparathyroidism. Vnitr Lek. 2000; 46:724-727.

Boneschi M., Erba M., Beretta L., Miani S., Bortolani E.M. Primary hyperparathyroidism and acute pancreatitis. A rare clinical association. Minerva Chir. 1999; 54:451-454.

Shimizu H., Kodama A. Hypercalcemia and pancreatitis as a first symptom of primary hyperparathyroidism adenoma: a case report. J Laryngol Otol. 1996; 110:602-603.

Nieves-Rivera F., Gonzalez-Pijem L. Primary hyperparathyroidism: an unusual cause of pancreatitis in adolescence. P R Health Sci J. 1995; 14:233-236.

Ginn D.R., Gate J., Tootle K., Salazar S., Watson S. Parathyroid adenoma manifested as pancreatitis and polyuria. South Med J. 1991; 61:396-398.

Maddern G.J., Fielding G.A., Knaus J.P., Zinng E., Blumgart L.H. A case of severe pancreatitis with parathyroid adenoma. Aust N Z J Surg. 1991; 84:1023-1025.

Abdullah M. Pancreatitis in primary hyperparathyroidism. Med J Malaysia. 2003; 58:600-603.

Meldahl I., Ljungstrom K.G., Wickerts C.J., Von Sigers K. Fulminant acute pancreatitis caused by a large parathyroid adenoma. Hyperparathyroidism was diagnosed after 5 years. Lakartidningen. 1999; 26:2603-2606.

Fraker D.L. Update on the management of parathyroid tumors. Curr Opin Oncol 2000, 12:41-48.

Wang C.A. Parathyroid reexploration. A clinical and pathological study of 112 cases. Ann Surg. 1977; 186:140145.

Lumachi F., Tregnaghi A., Zucchetta P., Marzola M.C., Cecchin D., Marchesi P., Fallo F., Bui F. Technetium99m sestamibi scintigraphy and helical CT together in patients with primary hyperparathyroidism: a prospective clinical study. Br J Radiol. 2004; 77:100-103.

Patrick N., Lenzo N.P., McCarthy M.C., Thompson I., Leedman P.J. Ectopic parathyroid adenoma localizedwith sestamibi SPECT and image-fused computed tomography. MJA. 2003; 179:485-487.

Serrano Vicente J., Rayo Madrid J.L., Luengo Perez L.M., Diaz Perez de Madrid J. 99m-Tc sestamibi scintigraphy in primary hyperparathyroidism. Importance of lateral projections using a pinhole collimator. Rev Esp Med Nucl. 2003; 22:403-409.

Perez-Monte J.E., Brown M.L., Shah A.N., Ranger N.T., Watson C.G., Carty S.A., Clarke M.R. Parathyroid adenomas: accurate detection and localization with Tc-99m sestamibi SPECT. Radiology. 1996; 201:85-91.

Casas A.T., Burke G.J., mansberger A.R., Wei J.P. Impact of technetium-99m-sestamibi localization on operative time and success of operations for primary hyperaparathyroidism. Am Surg. 1994; 60:12-17.

Udelsman R. Parathyroid imaging: the myth and the reality. Radiology 1996; 201:317-318.

Mariani G., Gulec S.A., Rubello D., Boni G., Puccini M., Pelizzo M.R., Manca G., Casara D., Sotti G., Erba P., Volteranni D., Giuliano A.E. Preoperative localization and radioguided parathyroid surgery. J Nucl Med. 2003; 44:1443-1458.

Neumann D.R., Esselstyn C.B., MacIntyre W.J., Go R.T., Obuchowski N.A., Chen E.Q., Licata A.A. Comparisonof FDG-PET and sestamibi SPECT in primary hyperparathyroidism. J Nucl Med. 1996; 37:1809-1815.

Barclay L. Unilateral approach for parathyroid surgery. Ann Surg. 2002; 236:543-551.

Анри Ж.Ф., Себаг Ф. Прикладная эмбриология паращитовидных желез. Материалы 11(13) симпозиума по хирургической эндокринологии. СПб., 2003; 62-69

Романчишен А.Ф., Матвеева З.С. Сочетание заболеваний щитовидной железы и бессимптомных аденом околощитовидных желез. Вестник хирургии. 2006

Черенько С.М. Первичный гиперпаратиреоз: основы патогенеза, диагностики и хирургического лечения: монография. Киев, 2011:148

Романчишен А.Ф., Матвеева З.С. Бессимптомные аденомы околощитовидных желез // Современные аспекты хирургической эндокринологии. Материалы XV Российского симпозиума по хирургической эндокринологии. Рязань, 2005:293-295