Biological activityspirit extraction from the duckweed small (Lemna minor L.) concerninginflammation process

Results of studying of chemical and mineral structure of a duckweed small (Lemnaminor L.), extended in the Tomsk region, allow to assume a wide spectrum of biologicalactivity of total extraction from the given medicinal raw materials. In the present researchstudying of biological activity spirit extraction from a duckweed small concerningan experimental inflammation of a miscellaneous genesis is spent. Research is spent tothe winter period on mice and rats males in weight 20-23 g and 200-250 g accordingly.The dried up spirit extract of a duckweed small on a physiological solution was enteredan animal per os by means of a probe within 5 days before experiment unitary a day in adose by of 100 or 200 mg/kg in the morning. In check experiments entered a physiologicalsolution (0,2 ml on 100 г weights of a body). Influence of an extract of a duckweed onprocess of an experimental inflammation studied on models carragenin hypostasis, sharpstress induced and ulcerogenic damages of a wall of a stomach (bandaging of pylorusstomach on 18 h). Intensity of an inflammation judged on percentage indicators of a gainand oppression of a hypostasis of finiteness of an animal; a condition of a wall of astomach estimated by quantity of destructive defeats and Pauls's index, and, definingacidity and proteolitic activity, estimated aggression of a contained stomach in relationto its mucous. Statistical procedures spent by means of applied package STATISTIC 6.0with use of average value of an analyzed indicator (M), a standard error of average (m)and nonparametric criterion Mann-Whitney (U-test). Thus, in experiment biological activityspirit extraction from a duckweed small concerning inflammatory process of a miscellaneousgenesis and localisations is shown. The extract had anti-inflammatory an effecton models carragenin and stress induced inflammations. However on model ulcerogenicdestructive damages of a wall of a stomach the duckweed extract has appeared notonly inefficient, but even increased quantity ulcers. Thus a preparation, without changingacidity of gastric juice, considerably raised it proteolitic activity.

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