Cyclotron production of 99Mo radionuclide by irradiation of zirconium target with alpha particle beam
The possibility of obtaining 99Mo by the nuclear reaction 96Zr (α, n ) on the R-7M cyclotron of Tomsk Polytechnic University was investigated. The energy of the α-particle beam was 27 MeV with a beam current of 13, 15 and 22 μA. As a target material, disks from natural zirconium with a diameter of 30 mm and a thickness of 1.5 mm were used. As a result of the conducted irradiation, the calculated 99Mo yield from 100% enriched 96Zr target was of the order of 1.62±0.15 MBq / μA-h, which closely coincides with the yield established in the works of other authors. The possibility of operating 99Mo in an amount sufficient to produce technetium-99m drugs at the regional level is shown.
Download file
Counter downloads: 107
Keywords
technetium-99m, моlibdenum-99, zirconium, cyclotron, циклотрон, технеций-99m, цирконий, молибден-99Authors
| Name | Organization | |
| Villa N.E. | National Research Tomsk Polytechnic University | nelsonvilla132@tpu.ru |
| Skuridin V.S. | National Research Tomsk Polytechnic University | skuridin@tpu.ru |
| Golovkov V.M. | National Research Tomsk Polytechnic University | golovkov@tpu.ru |
| Garapatski A.A. | National Research Tomsk Polytechnic University | garapatski@tpu.ru |
References
International Atomic Energy Agency. - Tech. Rep. Ser. No. 468. - IAEA, Vienna, 2009. - P. 261-264.
Скуридин В.С. Методы и технологии получения радиофармпрепаратов: учеб. пособие. - Томск: Изд-во ТПУ, 2012. - 92 с.
Emery C. and Strutt M. // British Geological Survey. - Internal Report IR/04/174. - 2004. - P. 12-15.
Link J., Krohn K., and O'Hara M. // Appl. Radiation and Isotopes. - 2017. - V. 122. - P. 211-214.
NuDat 2.7 database. National Nuclear Data Center (NNDC), Brookhaven. - 2018. URL: http://www.nndc.bnl.gov/nudat2/ (дата обращения 24.07.2018).
Pupillo G., Esposito J., Gambaccini M., et al. // J. Radioanal. Nucl. Chem. - 2014. - V. 302. - No. 2. - P. 913-916.
Rochman D., Koning A., Sublet J., and Fleming M. // Proc. Int. Conf. on Nuclear Data for Science and Technology. - 2016. URL: https://tendl.web.psi.ch/tendl_2017/tendl2017.html (дата обращения 09.07.2018).
Inglis E., Creech J., Deng Z., and Moynier F. // Chem. Geology. - 2018. - V. 493. - P. 544-552.
Chowdhury D., Pal S., Saha S., and Gangadharan S. // Nucl. Instrum. Methods Phys. Res. B. - 1995. - V. 103. - No. 3. - P. 264-266.
Aboudzadeh M., Aardaneh K., Aslani G., et al. // Appl. Radiation and Isotopes. - 2016. - V. 112. - P. 55-58.
Lisin V., Bogdanov A., Golovkov V., et al. // Rev. Sci. Instrum. - 2014. - V. 85. - No. 2. - P. 02C314-1-3.
Naafs M. // Biomedical Journal of Scientific & Technical Research (BJSTR). Review Article. - 2018. - V. 4. - No. 5. - P. 1-6.
Lokhov A., Cameron R., Westmacott C., et al. // Technical Report, Nuclear Energy Agency (NEA) and Organisation for Economic Co-operation and Development (OECD). - IAEA-TECDOC-1601, 2010. - P. 28- 31.
Mushtaq A., Iqbal M., Bokhari I., and Muhammad A. // Nucl. Instrum. Methods Phys. Res. - 2012. - V. 287. - P. 35-36.
Pillai M., Dash A., and Knapp F. // J. Nucl. Med. - 2013. - V. 54. - P. 313-318.
Tsechanski A., Bielajew A.F., Archambault J.P., and Mainegra-Hing E. // Nucl. Instrum. Methods Phys. Res. - 2016. - V. 366. - P.124-127.
Abbas K., Holzwarth U., Simonelli F., et al. // Nucl. Instrum. Methods Phys. Res. - 2012. - V. 278. - P. 20-22.
