Determination of viscoelastic characteristics of whole blood based on the method of low frequency piezotromboelastography
A theoretical and experimental study of the viscoelastic properties of whole blood at oscillating shear stresses was carried out. Based on ultrasonic elastography, a mathematical model has been developed, and a method for calculating the complex viscosity coefficient of whole blood during its coagulation. The complex viscosity index of whole blood and its real and imaginary parts were calculated. The calculated coefficient of blood viscosity at the beginning of the coagulation process is in good agreement with the data of rheometric measurements. The obtained results confirm the ability to use this approach to determine the viscoelastic properties of whole blood and analyze their dynamics during its coagulation in a regime as close as possible to an in vivo study.
Download file
Counter downloads: 108
Keywords
реология, неньютоновская жидкость, коагуляция цельной крови, динамика вязкости крови, rheology, non-Newtonian fluid, coagulation of whole blood, dynamics of blood viscosityAuthors
| Name | Organization | |
| Demkin V.P. | National Research Tomsk State University | demkin@ido.tsu.ru |
| Melnichuk S.V. | National Research Tomsk State University | osbereg@yandex.ru |
| Udut V.V. | National Research Tomsk State University; Tomsk National Research Medical Center of the Russian Academy of Sciences Scientific Research Institute of Pharmacology and Regenerative Medicine named after E.D. Goldberg | udutv@mail.ru |
| Tyutrin I.I. | Siberian State Medical University | ityutrinst@yandex.ru |
| Rudenko T.V. | National Research Tomsk State University | rudenko@ido.tsu.ru |
| Krinitsyna D.B. | National Research Tomsk State University | dbpic@mail.ru |
References
Cowan A.Q., Cho D.J., and Rosenson R.S. // Cardiovasc. Drugs. Ther. - 2012. - V. 26. - P. 339- 348.
Yilmaz F. and Gundogdu M.Y. // Korea-Australia Rheol. J. - 2008. - V. 20. - No. 4. - P. 197-211.
Rheology - new Concepts, Applications and Methods / ed. by Rajkumar Durairaj. - Pub. InTECH, 2013. - 106 p.
Anand M. and Rajagopal K.R. // Fluids. - 2017. - V. 2. - No. 3. - P. 35(9).
Udut V.V., Tyutrin I.I., Solovev M.A., et al. // Bull. Exp. Biol. Med. - 2015. - V. 2. - P. 162- 165.
Derjaguin B.V., Bazaron U.B., Lamazhapova Kh.D., et al. // Phys. Rev. A. - 1990. - V. 42. - P. 2255-2258.
Robertson A.M., Sequeira A., and Kameneva M.V. // Oberwolfach Seminars. - 2008. - V. 37. - P. 63-120.
Antonova N. // Biotechnology & Biotechnological Equipment. - 2012. - V. 26. - No. 5. - P. 3286-3291.
Brambatti V.M., de Andrade C.R., and Zaparoli E.L. // Proc. COBEM. 20th Int. Congress of Mechanical Engineering. Gramado, Brasil. November 15-20, 2009.
Sousa P.C., Carneiro J., Vaz R., et al. // Biorheology. - 2013. - V. 50. - P. 269-282.
Antonova N. // Series on Biomechanics. - 2012. - V. 27. - P. 44-50.
Thurston G.B. // Biophys. J. - 1972. - V. 12. - P. 1205-1217.
Marcinkowska-Gapinska A. and Kowal P. // Acta Phys. Polonica A: Acoustic and Biomed. Eng. - 2012. - V. 121. - No. 1. - P. A54-A56.
Тютрин И.И., Удут В.В. Низкочастотная пьезотромбоэластография цельной крови: алгоритмы диагностики и коррекции гемостазиологических расстройств. - Томск: Издательский Дом Томского государственного университета, 2016. - 170 с.
Hund S.J., Kameneva M.V., and Antaki J.F. // Fluids. - 2017. - V. 2. - No. 10. - P. 2-17.
Бутылин А.А., Пантелеев М.А., Атауллаханов Ф.И. // Российский химический журнал. - 2007. - Т. LI. - № 1. - С. 45-50.
Huang C.-C., Lin Y.-H., Liu T.-Y., et al. // J. Med. Biol. Eng. - 2011. - V. 31. - No. 2. - P. 79-86.
Dias J.D., Haney E.I., Mathew B.A., et al. // Arch. Pathol. Lab. Med. - 2017. - V. 141. - P. 569-577.
Thakur M. and Ahmed A.B. // Int. J. Periop. Ultras. Appl. Tech. - 2012. - V. 1. - No. 1. - P. 25-29.
Cardenas J.C., Rein-Smith C.M., and Church F.C. // Encyclopedia of Cell Biology. - 2016. - V. 1. - P. 714-722.
Демкин В.П., Мельничук С.В., Удут В.В. и др. // Изв. вузов. Физика. - 2019. - Т. 62. - № 6. - С. 47-56.
Ерофеев В.И., Кажаев В.В., Семерикова Н.П. Волны в стержнях. Дисперсия, диссипация, нелинейность. - М.: Физматлит, 2002. - 208 с.
Rashid F., Vartdal M., and Grue J. // J. Eng. Math. - 2011. - V. 70. - P. 281-295.
Derjaguina B.V., Bazarona U.B., Lamazhapovaa Kh.D., et al. // Prog. Surf. Sci. - 1992. - V. 40. - P. 462-465.
Vargaftik N. Справочник по теплофизическим свойствам газов и жидкостей. - M.: Наука, 1972. - 720 с.
Demelova T.S., Makarova D.N., Badmaev B.B., et al. // Res. Notes Phys. Faculty. - 2014. - V. 5. - P. 145304.
Badmaev B.B., Damdinov B.B., and Sanditov D.S. // Acoustics J. - 2004. - V. 50. - No. 2. - P. 1-5.
Koga K., Kimura T., Sakai R., et al. // J. Oleo Sci. - 2014. - V. 63. - No. 12. - P. 1309-1322.
Johnstona B.M., Johnstona P.R., Corneyb S., et al. // J. Biomechanics. - 2004. - V. 37. - P. 709-720.
