Relationship between the pore structure hierarchy and the physical and mechanical properties of calcium phosphate drug carriers | Izvestiya vuzov. Fizika. 2020. № 7. DOI: 10.17223/00213411/63/7/131

Relationship between the pore structure hierarchy and the physical and mechanical properties of calcium phosphate drug carriers

The relationship between the structural-morphological and physical-mechanical properties of macro-porous calcium phosphate (CaP) coatings on the surface of titanium implants was studied. Produced CaP coatings can be used as carriers and target drug delivery for biomedical applications. The regularities of formation of bulk (thickness of 15-130 µm) and rough (Ra = 1.7-8.5 µm) CaP coatings when deposited by the micro-arc oxidation (MAO) method were studied. The coatings had hierarchical porous structure and a uniform distribution of structural elements (spheres, pores) through the coating surface. The correlations between the value of the applied voltage, structural-morphological and physical-mechanical characteristics of CaP coatings were established. The value of the coating adhesion strength was determined with tensile test. Both cohesive and mixed adhesive-cohesive separations of MAO coating from the substrate were identified.

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Keywords

микродуговое оксидирование, кальций-фосфатное покрытие, сфероидальный структурный элемент, пористость, адгезионная прочность, micro-arc oxidation, calcium phosphate coating, spheroidal structural element, porosity, adhesion strength

Authors

Name	Organization	E-mail
Komarova E.G.	Institute of Strength Physics and Materials Science of SB RAS	katerina@ispms.ru
Sedelnikova M.B.	Institute of Strength Physics and Materials Science of SB RAS	smasha5@yandex.ru
Kazantseva E.A.	Institute of Strength Physics and Materials Science of SB RAS; National Research Tomsk State University	kati10_95@mail.ru
Uvarkin P.V.	Institute of Strength Physics and Materials Science of SB RAS	uvarkin@ispms.tsc.ru
Sharkeev Yu.P.	Institute of Strength Physics and Materials Science of SB RAS	sharkeev@ispms.tsc.ru

Всего: 5

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