Study of jung's module variations in a phantom model of lymphedematous tissue using optical coherent tomography
The paper presents the results of a phantom model study of the possibility of detecting tissue edema that occurs during acute and chronic inflammation, including lymphedema, using optical coherence tomography. Taking into account the fact that lymphedema is characterized by an increased content of intercellular fluid enriched with a high protein content, the phantom model was based on a change in the fluid content in muscle tissue. It is shown that the value of the Young's modulus of the phantom tissue monotonically decreases with an increase in the mass fraction of the liquid in it.
Download file
Counter downloads: 35
Keywords
tissue edema, lymphedema, optical tomography, Young's modulusAuthors
| Name | Organization | |
| Lokhin A.A. | National Research Tomsk State University | lokhin.a.a@gmail.com |
| Kistenev Y.V. | National Research Tomsk State University | yuk@iao.ru |
| Zakharova O.A. | National Research Tomsk State University | za.olga90@yandex.ru |
| Sandykova E.A. | Siberian State Medical University | katrin_nemchenko@mail.ru |
| Taletskiy A.V. | Tomsk Regional Oncology Center | talezkii@yandex.ru |
| Pavlova M.E. | Siberian State Medical University | pavme4604@gmail.com |
References
Lee B.B., Bergan J., Rockson S.G. Lymphedema. - London: Springer Verlag, 2011. - 570 p.
Warren A.G., Brorson H., Borud L.J., Slavin S.A // Ann. Plastic Surgery. - 2007. - V. 59. - No. 4. - P. 464-472.
Kayıran O., De La Cruz C., Tane K., Soran A. // Turkish J. Surgery. - 2017. - V. 33. - No. 2. - P. 51-57.
Tretbar L.L., Morgan C.L., Lee B., et al. Lymphedema. Diagnosis and Treatment. - London: Springer Verlag, 2008. - 81 p.
Anjali C., Raghuram R.P., Sung Yu C., et al. // Current Breast Cancer Reports. - 2019. - V. 11. - No. 1. - P. 365-372.
Melnikov D.V., Startseva O.I., Prudnikova D.K., et al. // Ann. Plastic Surgery. - 2018. - V. 13. - No. 1. - P. 38-50.
O'Donnell T.F., Rasmussen J.C., Sevick-Muraca E.M. // J. Vascular Surgery. Venous and Lymphatic Disorders. - 2017. - V. 5. - No. 2. - P. 261-273.
Unno N., Nishiyama M., Suzuki M., et al. // Eur. J. Vascular and Endovascular Surgery. - 2008. - V. 36. - No. 2. - P. 230-236.
Stoffels I., Joachim D., Pöppel T. // JAMA Surgery. - 2015. - V. 150. - No. 7. - P. 617-623.
Oğuz Kayıran, Carolyn De La Cruz, Kaori Tane, Atilla Soran // Turkish J. Surgery. - 2017. - V. 33. - No. 2. - P. 51-57.
Li H., Furst D.E., Jin H., et al. // Arthritis Research & Therapy. - 2018. - V. 20. - No. 181. - P. 1-8.
Ward L.C. // Lymphatic Research and Biology. - 2006. - V. 4. - No. 1. - P. 51-56.
Rutherford W.J. // J. Research. - 2011. - V. 6. - No. 2. - P. 56-60.
Nikolaev V.V., Vrazhnov D.A., Sandykova E.A, et al. // J. Phys. Conf. Ser. - 2019. - V. 1145. - No. 012043. - P. 1-7.
Kistenev Y.V., Nikolaev V.V., Kurochkina O.S., et al. // Biomed. Opt. Express. - 2019. - V. 10. - No. 7. - P. 3353-3368.
Sun C., Standish B., Yang V. // J. Biomed. Opt. - 2011. - V. 16. - No. 4. - P. 043001.
Lokhin A.A., Kistenev Y.V., Borisov A.V., et al. // Proc. SPIE. - 2019. - V. 11208. - P. 112080C-1-112080C-6.
Kirby M.A., Zhou K., Pitre J.J., et al. // J. Biomed. Opt. - 2019. - V. 24. - No. 9. - P. 096006-1-096006-16.
Li J., Liu C.H, Schill A., et al. // Proc. SPIE. - 2016. - V. 97101. - P. 97101A-1- 97101A-6.
Wang S., Larin K.V. // J. Biophotonics. - 2015. - V. 8. - No. 4. - P. 279-302.
Zaitsev V.Y., Matveev A.L., Matveev L.A., et al. // J. Innovative Opt. Health Sci. - 2017. - V. 10. - No. 6. - P. 1742006-1-1742006-13.
Krouskop T., Wheeler T., Kallel F., et al. // Ultrasonic Imaging. - 1998. - V. 20. - No. 4. - P. 260-274.
Kennedy B.F., Kennedy K.M., Chin L., et al. // J. Biomed. Opt. - 2014. - V. 5. - No. 9. - P. 3090-3102.
Chin L., Curatolo A., Kennedy F., et al. // Biomed. Opt. Express. - 2014. - V. 5. - No. 9. - P. 2913-2930.
Kennedy K.M., Ford C., Kennedy B.F., et al. // J. Biomed. Opt. - 2013. - V. 18. - No. 12. - P. 121508-1-121508-9.
Li J., Wang S., Manapuram R.K., et al. // J. Biomed. Opt. - 2013. - V. 18. - No. 4. - P. 121503-1-121503-6.
Zaitsev V.Y., Matveev L.A., Matveyev A.L., et al. // Laser Phys. Lett. - 2019. - V. 16. - No. 6. - P. 065601-065606.
En Li, Shuichi M., Shinnosuke A., Arata, et al. // Opt. Lett. - 2019. - V. 44. - No. 4. - P. 787-790.
Sun C., Standish B.A., Yang V.X.D. // J. Biomed. Opt. - 2011. - V. 16. - No. 4. - P. 043001-1-043001-13.
Qu Y.Q. // Investigative Ophthalmology & Visual Science. - 2018. - V. 59. - No. 1. - P. 455-461.
Gubarkova E.V., Sovetsky A.A., Zaitsev V.Y., et al. // Biomed. Opt. Express. - 2019. - V. 10. - No. 5. - P. 2244-2263.
Shinohara M., Sabra K., Gennisson L., et al. // Muscle Nerve. - 2010. - V. 42. - P. 438-441.
